NAD+ 500mg

NAD+ – 500mg.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell and is central to cellular metabolism and energy homeostasis. It plays a critical role in converting nutrients into cellular energy in the form of ATP through mitochondrial respiration, and serves as an essential cofactor for two key enzyme families: sirtuins and PARPs. Sirtuins are proteins linked to longevity that help regulate inflammation, support mitochondrial biogenesis, maintain DNA stability, and improve cellular stress response. PARPs are enzymes responsible for detecting and repairing damaged DNA strands, protecting cells from aging-related mutations. NAD+ levels naturally decline with age, correlating with reduced metabolic function, impaired DNA repair capacity, and increased susceptibility to oxidative stress. Research by Dr. David Sinclair at Harvard Medical School has demonstrated that restoring NAD+ levels in animal models through precursors like NMN may improve mitochondrial function, enhance DNA repair, increase muscle endurance, and partially reverse age-related tissue decline. NAD+ represents a foundational molecule in longevity and cellular resilience research.